YIGSR-Lys(N3)

SKU: orb3142549

Description

YIGSR-Lys(N3) is a peptide that inhibits the tumor growth and metastasis of leukemia cells. This compound interferes with the interaction between cells and laminin I by blocking a 67 kDa laminin-binding protein, thereby reducing shear-induced eNOS expression in laminin cells. As a click chemistry reagent, YIGSR-Lys(N3) contains an azide group that undergoes copper-catalyzed azide-alkyne cycloaddition (CuAAC) with alkynyl-containing molecules. Additionally, it can engage in strain-promoted azide-alkyne cycloaddition (SPAAC) reactions with molecules bearing DBCO or BCN groups.

Research Area

Immunology & Inflammation

Key Properties

• Target: NO Synthase
• CAS Number: 2415188-59-7
• MW: 748.83
• Formula: C₃₂H₅₂N₁₂O₉
• SMILES: [C@@H](NC([C@@H](NC(CNC([C@@H](NC([C@H](CC1=CC=C(O)C=C1)N)=O)[C@H](CC)C)=O)=O)CO)=O)(C(N[C@@H](CCCCN=[N+]=[N-])C(O)=O)=O)CCCNC(=N)N

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

NO Synthase