YHS-12

SKU: orb2815805

Description

YHS-12 is an ionizable cationic lipid (pKa 6.506) used to formulate macrophage-targeted LNPs for co-delivery of mRNA and siRNA. These LNPs enhance anti-MRSA phagocytosis in vitro in RAW 264.7 and BMDM cells and improve survival in murine sepsis models, demonstrating utility in immunotherapy and infectious disease research.

Key Properties

• CAS Number: 2959463-68-2
• MW: 873.51
• Formula: C₅₆H₁₁₂N₄O₂
• SMILES: N(CCNC(/C=C/C(NCCN(CCCCCCCCCCCC)CCCCCCCCCCCC)=O)=O)(CCCCCCCCCCCC)CCCCCCCCCCCC

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

172195219