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Catalog Number | orb1297172 |
---|---|
Category | Small Molecules |
Description | Yangambin |
CAS Number | 13060-14-5 |
Purity | 98.02% |
MW | 446.49 |
SMILES | O(C)C=1C=C([C@@H]2[C@@]3([C@@]([C@H](OC3)C4=CC(OC)=C(OC)C(OC)=C4)(CO2)[H])[H])C=C(OC)C1OC |
Formula | C24H30O8 |
Biological Activity | Yangambin is a selective antagonist of the cardiovascular effects of platelet activating factor (PAF); it has hypotensive effect, which is probably due to a peripheral vasodilatation that involves, at least, the inhibition the Ca2+ influx through voltage-gated Ca2+ channels. Yangambin has central nervous system activity, it presents a depressant activity in the open field, forced swimming and pentobarbital sleeping time tests. |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
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