Yadanzioside G

SKU: orb1684149

Description

Yadanzioside G is a quassinoid terpenoid isolated from Brucea javanica, exhibiting antipancreatic cancer activity. It functions as an inhibitor of the Mycobacterium tuberculosis InhA enzyme, demonstrating potential for anti-tuberculosis drug development in both in vitro and in vivo research contexts.

Research Area

Infectious Disease & Virology

Key Properties

• CAS Number: 95258-17-6
• MW: 768.76
• Purity: 99.97% (May vary between batches)
• Formula: C₃₆H₄₈O₁₈
• SMILES: C(OC)(=O)[C@]12[C@]3([C@]4([C@@]([C@]5(C)[C@@](C[C@]4(OC(=O)[C@@H]3OC(/C=C(/C(OC(C)=O)(C)C)\C)=O)[H])([C@H](C)C(=O)C(O[C@@H]6O[C@H](CO)[C@@H](O)[C@H](O)[C@H]6O)=C5)[H])([C@@H](O)[C@@H]1O)[H])CO2)[H]
• Target: Antibacterial

Bioactivity

• In Vitro:
  Methods: PANC-1 and SW1990 cells were treated with Yadanzioside G (0.01-100 μg/mL, 72 hours) and SRB analysis was performed. Results: The IC50 values ​​of Yadanzioside G for PANC-1 and SW1990 cells were 60 μg/mL and greater than 10 μg/mL.
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Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Yadanzioside G

Compound Identifiers

PubChem CID

101659161