Y502-2304

SKU: orb3173362

Description

Y502-2304 is a c-MycG-quadruplex stabilizer that exhibits potent antiproliferative activity in multiple myeloma (MM) cells. It downregulates c-Myc mRNA and protein expression and induces apoptosis in MM cells, as characterized by increased γH2AX levels, elevated reactive oxygen species (ROS) production, and mitochondrial dysfunction. Additionally, Y502-2304 significantly inhibits tumor growth in xenograft MM models and is useful for studying multiple myeloma.

Research Area

Cell Biology, Immunology & Inflammation

Key Properties

• CAS Number: 741278-95-5
• MW: 369.36
• Formula: C₁₆H₁₁N₅O₄S
• SMILES: O=C(OC)C=1SC=2N=CN3N=C(N=C3C2C1C)C=4C=CC(=CC4)N(=O)=O
• Target: Apoptosis,c-Myc,ROS

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

Apoptosis,c-Myc,ROS