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Catalog Number | orb1219732 |
---|---|
Category | Small Molecules |
Description | Y-33075 dihydrochloride is a selective inhibitor of ROCK(IC50 of 3.6 nM).Y-33075 (Y-39983) is a potent inhibitor of ROCK(IC50 of 3.6 nM). Y-33075 also inhibits PKC and CaMKII more potently than Y-27632(IC50s of Y-27632 and Y-33075 for PKC are 9.0 μM and 0.42 μM, respectively), whereas the IC50s of Y-27632 and Y-33075 for CaMKII are 26 μM and 0.81 μM, respectively. |
Target | ROCK|PKC|CaMKII |
Purity | > 98% (HPLC) |
MW | 353.3 |
CAS Number | 173897-44-4 |
Formula | C16H18Cl2N4O |
Storage | Storage temperature: -20°C. Stability: ≥ 2 years |
Note | For research use only |
99.43% | |
173897-44-4 | |
353.25 | |
C16H18Cl2N4O |