XYD049

SKU: orb2945069

Description

XYD049 (compound 7d) is a CRBN-based molecular glue degrader of GSPT1 with potent activity against MYC-driven castration-resistant prostate cancer (CRPC). It demonstrates strong in vitro growth inhibition of 22Rv1 cells and in vivo antitumor efficacy by downregulating key oncoproteins like AR-v7 and c-Myc.

Research Area

Pharmacology & Drug Discovery

Key Properties

• CAS Number: 3006788-11-7
• MW: 811.656
• Formula: C₃₅H₃₅BrN₆O₁₀S
• SMILES: O=C(NCCCCCNC1=CC=CC=2C(=O)N(C(=O)C12)C3C(=O)NC(=O)CC3)COC4=CC=5ON=C(C5C=C4NS(=O)(=O)C6=CC(Br)=CC=C6OC)C
• Target: Molecular Glues

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

170353301