XY-52

SKU: orb1944004

Description

Compound 32 (XY-52) is a small molecule ST2 inhibitor with IC₅₀ values of 5.68 μM (AlphaLISA) and 4.59 μM (HEK-Blue). In a GVHD mouse model, it promotes proinflammatory T-cell proliferation and reduces plasma sST2 and IFNγ levels, supporting its use in immunology and inflammation research.

Research Area

Immunology & Inflammation

Key Properties

• MW: 499.65
• Formula: C₃₀H₃₇N₅O₂
• SMILES: CC1=CC([N+]([O-])=O)=CC=C1C2=CC=C(CN3C(C4=CC=CC(N5CC(CC6)NC6C5)=C4)CCC3)N2CC
• Target: Others,Interleukin

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

168510351