XRD-0394

SKU: orb2565042

Description

XRD-0394 is a highly effective and selective dual inhibitor of ATM and DNA-PKcs, exhibiting oral bioactivity. It notably increases tumor cell destruction both in vitro and in vivo when combined with therapeutic ionizing radiation. Furthermore, XRD-0394 enhances the efficacy of PARP and topoisomerase I inhibitors in vitro.

Key Properties

• CAS Number: 2595308-10-2
• MW: 527.61
• Formula: C₂₆H₃₀FN₅O₄S
• SMILES: O=C1C2(C=3C=4C(N=CC3N1C)=CC(F)=C(C4)C=5C=C(NS(C)(=O)=O)C(OCCNC(C)C)=NC5)CCC2
• Target: DNA-PK,ATM/ATR

Storage & Handling

• Storage: -20°C
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

DNA-PK,ATM/ATR