XOR/URAT1-IN-1

SKU: orb2564463

Description

Compound II15, known as XOR/URAT1-IN-1, serves as a dual inhibitor targeting xanthine oxidoreductase (XOR) and uric acid transporter 1 (URAT1), exhibiting IC50 values of 6 nM and 12.9 μM, respectively. This compound effectively reduces uric acid levels in a mouse model of acute hyperuricemia induced by potassium oxonate and hypoxanthine.

Research Area

Metabolism Research, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 2810137-86-9
• MW: 340.76
• Formula: C₁₈H₁₃ClN₂O₃
• SMILES: O=C(O)C=1C=CC(=CC1O)C2=CN=CC(=C2)NC=3C=CC=C(Cl)C3
• Target: OAT,Xanthine Oxidase

Storage & Handling

• Storage: -20°C
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

OAT,Xanthine Oxidase