XMD-12

SKU: orb1738311

Description

XMD-12 (Aurora-IN-1) is a potent, small-molecule inhibitor of Aurora kinases A, B, and C with IC50 values of 5.6, 18.4, and 24.6 nM, respectively. This compound is a valuable research tool for studying mitotic regulation and has been utilized in both cellular and in vivo models of cancer to investigate Aurora kinase function and therapeutic potential.

Research Area

Cell Biology, Epigenetics & Chromatin

Key Properties

• CAS Number: 1234481-08-3
• MW: 430.5
• Purity: 99.94% (May vary between batches)
• Formula: C₂₄H₂₆N₆O₂
• SMILES: O=C1C=2C=CC=CC2N(C3=NC(=NC=C3N1C)NC4=CC=C(C=C4)N5CCC(O)CC5)C
• Target: Aurora Kinase

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

54592204