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XM-U-14

SKU: orb2664190

Description

XM-U-14 is a potent and selective PROTAC USP7 degrader with a DC50 of 0.74 nM in RS4;11 cells. It stabilizes p53, induces cell cycle arrest and apoptosis, and demonstrates potent anti-proliferative activity in ALL cell lines, supporting its investigation in oncology research for hematological malignancies.

Research Area

Cell Biology, Molecular Biology, Pharmacology & Drug Discovery, Protein Biochemistry

Images & Validation

Key Properties

TargetPROTACs,Apoptosis,MDM-2/p53,DUB

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
Quality Guarantee

Quality Guarantee

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Protocol Information