XL-418

SKU: orb1741003

Description

XL-418 is an orally bioavailable small molecule inhibitor targeting AKT (PKB) and p70S6K, key kinases downstream of PI3K that are frequently overactive in cancers. Its dual inhibition promotes tumor cell apoptosis and suppresses protein translation, making it a valuable tool for investigating PI3K pathway biology in both cellular and animal models of oncology research.

Key Properties

• CAS Number: 871343-09-8
• MW: 609.48
• Formula: C₂₆H₃₂BrF₃N₈O
• SMILES: BrC=1C2=C(N=CN=C2NN1)N3CCN(CC3)C4=CC(C(CCC(F)(F)F)=O)=CC(NCCN5CCCC5)=C4C
• Target: Others

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

56963011