XL-188

SKU: orb1739790

Description

XL-188 is a potent and selective USP7 inhibitor with low nanomolar IC50 values, promoting HDM2 degradation and p53/p21 stabilization. This tool compound is used in oncology research to study the p53 pathway in cellular and biochemical assays.

Research Area

Cell Biology, Molecular Biology, Protein Biochemistry

Key Properties

• CAS Number: 2305045-76-3
• MW: 574.71
• Formula: C₃₂H₄₂N₆O₄
• SMILES: O=C1C=2C(=CC(NC(CCN3CCN(C)CC3)=O)=CC2)N=CN1CC4(O)CCN(C(C[C@@H](C)C5=CC=CC=C5)=O)CC4
• Target: DUB,Others

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

131953451