XIAP BIR2/BIR2-3 inhibitor-3

SKU: orb2565047

Description

This potent dual inhibitor of the XIAP BIR2 and BIR2-3 domains exhibits sub-nanomolar activity (IC50 < 1 nM). It is a valuable research tool for studying apoptosis resistance mechanisms in cancer, with applications in both in vitro biochemical assays and cellular studies.

Research Area

Cell Biology, Pharmacology & Drug Discovery; Cell Biology

Key Properties

• CAS Number: 1434125-52-6
• MW: 1712
• Formula: C₈₆H₁₀₆N₁₈O₁₆S₂
• SMILES: C([C@@H](NC([C@@H](NC)C)=O)C(C)(C)C)(=O)N1[C@]2(C[C@@](C1)(N3C=C(N=N3)COC=4C=CC(=CC4)C[C@@H](C(NS(=O)(=O)C5CC5)=O)NC(=O)[C@H](CC=6C7=C(C=CC6)C=CC=C7)NC(=O)[C@@]8(C[C@](N9C=C(COC=%10C=CC(C[C@@H](C(NS(=O)(=O)C%11CC%11)=O)NC(=O)[C@H](CC=%12C%13=C(C=CC%12)C=CC=C%13)NC2=O)=CC%10)N=N9)(CN8C([C@@H](NC([C@@H](NC)C)=O)C(C)(C)C)=O)[H])[H])[H])[H]
• Target: IAP

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

169494450