XIAP BIR2/BIR2-3 inhibitor-2

SKU: orb2565048

Description

This small molecule is a potent dual inhibitor of XIAP's BIR2 and BIR2-3 domains, exhibiting sub-nanomolar IC50 values. It serves as a valuable research tool for investigating apoptosis pathways and has been utilized in both in vitro and in vivo cancer studies.

Research Area

Cell Biology, Pharmacology & Drug Discovery; Cell Biology

Key Properties

• CAS Number: 1609384-83-9
• MW: 1529.75
• Formula: C₈₀H₉₆N₂₀O₁₂
• SMILES: C([C@@H](NC([C@@H](NC)C)=O)C(C)(C)C)(=O)N1[C@]2([C@](N3C=C(N=N3)COC=4C=CC(=CC4)C[C@@H](C(O)=O)NC(=O)[C@H](CC5=CC6=C(C=C5)C=CC=C6)NC(=O)[C@@]7([C@](N8C=C(COC=9C=CC(C[C@H](NC(=O)[C@H](CC%10=CC%11=C(C=C%10)C=CC=C%11)NC2=O)C=%12NN=NN%12)=CC9)N=N8)(CCN7C([C@@H](NC([C@@H](NC)C)=O)[C@@](C)(C)C)=O)[H])[H])(CC1)[H])[H]
• Target: Others,IAP

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

118429219