Xanthopurpurin

SKU: orb1297174

Description

Xanthopurpurin is a bioactive small molecule exhibiting antiviral activity, notably inhibiting rotavirus replication in MA-104 cells by enhancing virus-induced apoptosis. It also demonstrates potent inhibition of collagen-induced platelet aggregation, making it a compound of interest for virology and cardiovascular research.

Research Area

Infectious Disease & Virology, Protein Biochemistry

Key Properties

• CAS Number: 518-83-2
• MW: 240.21
• Purity: 98.05% (May vary between batches)
• Formula: C₁₄H₈O₄
• SMILES: Oc1cc(O)c2C(=O)c3ccccc3C(=O)c2c1
• Target: MMP,Antifection,Platelet aggregation,HIV Protease

Bioactivity

• In Vitro:
  The cytotoxicity of RCAP toward MA-104 cells was evaluated using the WST-8 assay. Colloidal gold method and real time polymerase chain reaction (qPCR) assay were used to confirm the findings of the antiviral assay. Then, 4',6-diamidino-2-phenylindole (DAPI) staining method was subsequently used to investigate the mode of death among the cells. And the representative components of aqueous extract were isolated and identified. It was shown that both the viability of MA-104 cells and the viral load were reduced with increasing concentration of the extract. DAPI staining showed that virus-induced apoptosis was the cause of the low cell viability and viral load, an effect which was accelerated with incubation in the aqueous herbal extract. The major compounds postulated to exhibit this activity were isolated from the aqueous herbal extract and identified to be compounds Xanthopurpurin and Vanillic Acid

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Antifection, inhibit, Inhibitor, Purpuroxanthin, Platelet aggregation, Plateletaggregation, Xanthopurpurin

Compound Identifiers

PubChem CID

196978