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X15695

SKU: orb3173321

Description

X15695 is a selective and orally active estrogen receptor (ERα) degrader, acting as a ligand for the aryl hydrocarbon receptor (AHR). It facilitates the formation of a complex between AHR and ERα, promoting proteasomal degradation. X15695 inhibits the proliferation of breast cancer cells, induces cell cycle arrest, and triggers apoptosis, making it useful for breast cancer research.

Research Area

Cell Biology, Immunology & Inflammation, Metabolism Research

Images & Validation

Key Properties

CAS Number353258-25-0
MW314.665
FormulaC14H7ClF4N2
SMILESFC1=CC=C(C=C1)C1=CN2C=C(C=C(Cl)C2=N1)C(F)(F)F
TargetApoptosis,Estrogen Receptor/ERR,MDM-2/p53,Aryl Hydrocarbon Receptor

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Protocol Information