WZ4002-hydroxy

SKU: orb1985188

Description

WZ4002-hydroxyl, a WZ4002 analogue with hydroxyl replacing methoxy, is identified in 50% of gefitinib- or erlotinib-resistant patients. WZ4002 features a distinct covalent pyrimidine scaffold. It is used in research on EGFR-driven cancers, including in vitro and in vivo studies of resistance mechanisms.

Key Properties

• MW: 480.95
• Formula: C₂₄H₂₅ClN₆O₃
• SMILES: C=CC(NC1=CC=CC(OC2=NC(NC3=CC=C(C=C3O)N4CCN(CC4)C)=NC=C2Cl)=C1)=O
• Target: Others

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

154985414