WZ3146

• Catalog Number: orb1223387
• Category: Small Molecules
• Description: WZ3146 is a mutant-selective irreversible inhibitor of EGFR(L858R) and EGFR(E746_A750) with IC50 of 2 nM and 2 nM; does not inhibit ERBB2 phosphorylation (T798I).
• Target: EGFR (E746_A750)| EGFR (E746_A750/T790M)| EGFR (L858R)| EGFR (L858R/T790M)
• Purity: > 98% (HPLC)
• MW: 465
• CAS Number: 1214265-56-1
• Formula: C₂₄H₂₅ClN₆O₂
• Storage: Storage temperature: -20°C. Stability: ≥ 2 years
• Note: For research use only