WYE-687 dihydrochloride

SKU: orb1745010

Description

WYE-687 dihydrochloride is an ATP-competitive inhibitor of mTOR, demonstrating potent activity with an IC50 value of 7 nM. It effectively suppresses the activation of both mTORC1 and mTORC2. Additionally, WYE-687 exhibits inhibitory effects on PI3Kα and PI3Kγ, with IC50 values of 81 nM and 3.11 μM, respectively.

Research Area

Signal Transduction

Images & Validation

−

Key Properties

−

CAS Number	1702364-87-1
MW	601.53
Formula	C₂₈H₃₄Cl₂N₈O₃
SMILES	Cl.Cl.O=C(OC)NC=1C=CC(=CC1)C=2N=C3C(C=NN3C4CCN(CC=5C=NC=CC5)CC4)=C(N2)N6CCOCC6
Target	PI3K,Others,mTOR

Storage & Handling

−

Storage	-20°C
Disclaimer	For research use only

Quality Guarantee

Explore bioreagents carefree to elevate your research. All our products are rigorously tested for performance. If a product does not perform as described on its datasheet, our scientific support team will provide expert troubleshooting, a prompt replacement, or a refund. For full details, please see our Terms & Conditions and Buying Guide. Contact us at [email protected].

Compound Identifiers

PubChem CID

90488926 ↗

Key Properties

−

No computed properties available.

Documents Download

Datasheet

Product Information

Download

Request a Document

Protocol Information

Find More Protocols