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WYE-687 dihydrochloride

SKU: orb1745010

Description

WYE-687 dihydrochloride is a potent, ATP-competitive mTOR inhibitor (IC50 = 7 nM) that suppresses both mTORC1 and mTORC2 complexes, with additional activity against PI3Kα and PI3Kγ. This compound is utilized in cancer research to study mTOR and PI3K signaling pathways in cellular and animal models of tumor growth and proliferation.

Research Area

Signal Transduction

Images & Validation

Key Properties

CAS Number1702364-87-1
MW601.53
FormulaC28H34Cl2N8O3
SMILESCl.Cl.O=C(OC)NC=1C=CC(=CC1)C=2N=C3C(C=NN3C4CCN(CC=5C=NC=CC5)CC4)=C(N2)N6CCOCC6
TargetOthers,mTOR,PI3K

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Key Properties

No computed properties available.

Protocol Information