WWP1/2-IN-1

SKU: orb2695671

Description

WWP1/2-IN-1 (compound 11) is a dual inhibitor of the E3 ubiquitin ligases WWP1 and WWP2, exhibiting IC50 values of 32.7 µM and 269.2 µM, respectively. This small molecule is a useful research tool for probing ubiquitination pathways in cellular and biochemical studies, including investigations into cancer and developmental biology.

Research Area

Protein Biochemistry

Key Properties

• MW: 335.21
• Formula: C₁₁H₁₂Cl₂N₄O₂S
• SMILES: N(C(OCC1=CC=C(NC([C@@H](NC([C@@H](NC(CCOCCOCCOCCNC(CCC(=O)N2C=3C(C#CC=4C(C2)=CC=CC4)=CC=CC3)=O)=O)[C@@H](C)C)=O)CCCNC(N)=O)=O)C=C1)=O)[C@@H]5C6=C7C(C=8N(C7)C(=O)C9=C(C8)[C@](CC)(O)C(=O)OC9)=NC=%10C6=C(CC5)C(C)=C(F)C%10
• Target: E1/E2/E3 Enzyme,Others

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

172652617