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WS-384

SKU: orb3134030

Description

WS-384 is an orally active dual inhibitor of LSD1 and DCN1-UBC12 protein-protein interactions, with IC50 values of 338.79 nM and 14.81 nM, respectively. It exhibits anticancer properties, causing cell cycle arrest, DNA damage, and inducing apoptosis (apoptosis). WS-384 can be applied in research on non-small cell lung cancer (NSCLC).

Research Area

Cell Biology, Epigenetics & Chromatin, Molecular Biology, Protein Biochemistry

Images & Validation

Key Properties

CAS Number2247544-03-0
MW542.91
FormulaC18H21BrClN9S2
SMILESCl.BrC1=CC=C(C=C1)CSC=2N=C3N=C(C=C(SC4=NN=NN4CCN(C)C)N3N2)C
TargetDNA/RNA Synthesis,E1/E2/E3 Enzyme,Apoptosis,Caspase,Histone Demethylase

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Protocol Information