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WRN inhibitor 19

SKU: orb3135427

Description

WRN inhibitor 19 (Compound 40) is a WRN helicase inhibitor with an IC50 of 3.7 nM. It exhibits selective antiproliferative activity in WRN-dependent cancer cells by competitively binding to the ATP site to inhibit WRN helicase function, inducing DNA damage and causing cell cycle arrest. WRN inhibitor 19 is applicable for research in WRN-dependent cancers.

Research Area

Cell Biology, Epigenetics & Chromatin; Pharmacology & Drug Discovery, Molecular Biology

Images & Validation

Key Properties

TargetDNA/RNA Synthesis

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Protocol Information