WRN inhibitor 15

SKU: orb2814224

Description

WRN inhibitor 15 (Compound 9) is a small molecule targeting the Werner syndrome helicase, exhibiting antitumor activity with IC50 values of 37.9-46.6 μM in prostate and cervical cancer cell lines. It is a useful chemical probe for in vitro studies of DNA damage response and synthetic lethality in microsatellite unstable cancers.

Research Area

Cell Biology, Epigenetics & Chromatin; Pharmacology & Drug Discovery, Molecular Biology

Key Properties

• MW: 301.29
• Formula: C₁₆H₁₃F₂N₃O
• Target: DNA/RNA Synthesis

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

DNA/RNA Synthesis