WRN inhibitor 12

SKU: orb2695235

Description

WRN inhibitor 12 (compound 5) is a small molecule that selectively targets and inhibits the Werner syndrome ATP-dependent helicase (WRN). This tool compound is used in vitro to study DNA repair mechanisms and synthetic lethality in microsatellite unstable (MSI) cancer models.

Research Area

Cell Biology, Epigenetics & Chromatin; Pharmacology & Drug Discovery, Molecular Biology

Key Properties

• CAS Number: 3044040-29-8
• MW: 728.12
• Formula: C₃₃H₃₃ClF₃N₉O₅
• SMILES: O=C(C1=NC=NC(=C1O)C)N2CC3N(C=4C(=O)N5N=C(N=C5N(C4CC)CC(=O)NC6=CC=C(C=C6Cl)C(F)(F)F)C7=CCOCC7)C(C2)CC3
• Target: DNA/RNA Synthesis

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

172652663