WR 30090

SKU: orb3174535

Description

WR 30090 (Compound 37) is a broad-spectrum antimalarial agent that operates independently of the classical antifolate pathway. It shows significant activity against various strains of Plasmodium falciparum, both chloroquine-sensitive and -resistant, notably effective against the highly resistant Vietnamese strain. In rodent malaria tests, WR 30090 demonstrated high activity with a minimum effective dose of 5 mg/kg and a minimum curative dose of 20 mg/kg. This compound is useful for studying acute malaria.

Research Area

Infectious Disease & Virology

Key Properties

• CAS Number: 19160-62-4
• MW: 514.31
• Formula: C₂₅H₂₈Cl₄N₂O
• SMILES: ClC=1C=C(Cl)C2=NC(=CC(=C2C1)C(O)CN(CCCC)CCCC)C=3C=CC(Cl)=C(Cl)C3
• Target: Parasite

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

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Gene Symbol

Parasite