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Wnt/β-catenin agonist 4

SKU: orb1689227

Description

Wnt/β-catenin agonist 4

Research Area

Signal Transduction, Stem Cell & Developmental Biology, Stem Cell & Developmental Biology; Pharmacology & Drug Discovery

Images & Validation

Key Properties

CAS Number912784-79-3
MW314.31
Purity99.96% (May vary between batches)
FormulaC16H15FN4O2
SMILESFc1ccc(cc1)-c1cc(no1)C(=O)NCCCn1ccnc1
TargetWnt/beta-catenin
SolubilityDMSO:112.5 mg/mL (357.93 mM)

Bioactivity

In Vitro
Wnt/β-catenin agonist 4, identified also as Derivative 83, demonstrates significant biological activity by enhancing ALP (alkaline phosphatase) activity by 2848% during the differentiation of the ST2 cell line into osteoblasts at a concentration of 11 μM over 4 days. Additionally, at a concentration of 120 μM for 24 hours, it exhibits a 1049% increase in β-catenin activity in HEK293 and SW480 cells.

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

βcatenin, Wnt/β-catenin, Wnt/b-catenin, Wnt/betacatenin, Wnt, betacatenin, beta-catenin, bcatenin

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Key Properties

No computed properties available.

Protocol Information

Available Sizes

Select a size below

1 mg
$ 70.00
5 mg
$ 110.00
1 ml x 10 mM (in DMSO)
$ 120.00
10 mg
$ 150.00
25 mg
$ 240.00
50 mg
$ 370.00
100 mg
$ 580.00
200 mg
$ 800.00
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