Wnt/β-catenin agonist 2

SKU: orb1690129

Description

Wnt/β-catenin agonist 2 is a potent small molecule activator of the canonical Wnt signaling pathway. It is widely utilized in both in vitro and in vivo research to investigate the role of Wnt/β-catenin signaling in cancer metastasis, stem cell biology, and tissue regeneration.

Research Area

Signal Transduction, Stem Cell & Developmental Biology, Stem Cell & Developmental Biology; Pharmacology & Drug Discovery

Key Properties

• CAS Number: 943820-93-7
• MW: 272.26
• Purity: 99.58% (May vary between batches)
• Formula: C₁₃H₁₂N₄O₃
• SMILES: O=C(NCCn1cccn1)c1cc(on1)-c1ccco1
• Target: Wnt/beta-catenin,GSK-3
• Solubility: DMSO:55 mg/mL (202.01 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (7.35 mM)

Bioactivity

• In Vitro:
  Wnt/β-catenin agonist 2 acts as a stimulator of β-Catenin in the SW480 cell line, enhancing its activity. Moreover, it has been observed that Wnt/β-catenin agonist 2 exerts an influence on the differentiation of ST2 cells, promoting their transformation into osteoblasts .
  Read more...

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

GSK-3, GSK3, bcatenin, beta-catenin, betacatenin, Wnt, Wnt/β-catenin, Wnt/beta-catenin agonist 2, Wnt/β catenin agonist 2, Wnt/b-catenin agonist 2, Wnt/b-catenin, Wnt/betacatenin, Wnt/βcatenin agonist 2, Wnt/β-catenin agonist 2, βcatenin

Compound Identifiers

PubChem CID

24740085