WM-586

SKU: orb2278184

Description

WM-586 is a potent and selective covalent inhibitor of the WDR5-MYC protein-protein interaction, exhibiting an IC50 of 101 nM in HTRF assays. This compound is a valuable chemical probe for oncology research, enabling the study of MYC-driven transcriptional programs in both cellular and in vivo models of cancer.

Research Area

Epigenetics & Chromatin

Key Properties

• CAS Number: 2894832-05-2
• MW: 467.47
• Formula: C₂₀H₂₀F₃N₅O₃S
• SMILES: FC1=C(C[C@@H](CCCC)C(=O)NC2=NN=NN2)C(F)=CC(C2C=CC=C(S(=O)(=O)F)C=2)=C1
• Target: Histone Methyltransferase

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

167312325