WK88-1

SKU: orb2665498

Description

WK88-1 is a small molecule Hsp90 inhibitor that degrades key oncogenic drivers like EGFR, ErbB2, and ErbB3. It demonstrates potent anti-proliferative and pro-apoptotic activity in resistant models such as H1975 cells, supporting its use in cancer research for investigating targeted protein degradation and overcoming therapeutic resistance.

Research Area

Cell Biology, Metabolism Research, Signal Transduction

Key Properties

• CAS Number: 958888-32-9
• MW: 502.64
• Formula: C₂₈H₄₂N₂O₆
• SMILES: CO[C@H]1CC\C=C(C)/C(=O)NC2=CC(C[C@@H](C)C[C@H](OC)[C@H](O)[C@@H](C)\C=C(C)\[C@H]1OC(N)=O)=CC=C2
• Target: Apoptosis,HSP

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

176419167