WJ460

SKU: orb1307607

Description

WJ460 is a potent and selective myoferlin inhibitor. It demonstrates anti-metastatic properties in breast cancer models, as evidenced by its ability to suppress cell migration and invasion in vitro and reduce metastatic burden in vivo. This small molecule is a valuable research tool for studying myoferlin's role in cancer progression.

Key Properties

• CAS Number: 1415251-36-3
• MW: 460.59
• Purity: 99.12% (May vary between batches)
• Formula: C₂₇H₂₈N₂O₃S
• SMILES: COc1ccccc1N1C(SCC1=O)c1cccc(c1)C(=O)NCCCCc1ccccc1
• Target: Others
• Solubility: DMSO:200 mg/mL (434.23 mM)

Bioactivity

• In Vivo:
  In a spontaneous metastasis model, WJ460 inhibits angiogenesis, breast tumor growth, and spontaneous metastasis .
• In Vitro:
  WJ460 dose-dependently blocks breast cancer cell invasion through Collagen I(IC50: 43.37 nM in MDA-MB-231 and 36.40 nM in BT549 cells).

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

MYOF, myoferlin, WJ460, WJ-460, WJ 460

Compound Identifiers

PubChem CID

134820567