Withanolide B

SKU: orb1684157

Description

Withanolide B, a natural compound from Withania somnifera, stimulates osteogenesis in hBMSCs by activating ERK1/2 and Wnt/β-catenin signaling, which supports bone regeneration. It also binds the PARP-1 catalytic domain, making it a useful research tool for studying bone healing mechanisms in both cellular and animal models.

Research Area

Epigenetics & Chromatin, Molecular Biology, Signal Transduction, Stem Cell & Developmental Biology

Key Properties

• CAS Number: 56973-41-2
• MW: 454.6
• Formula: C₂₈H₃₈O₅
• SMILES: [H][C@@]1(CC[C@@]2([H])[C@]3([H])[C@@H]4O[C@@H]4[C@@]4(O)CC=CC(=O)[C@]4(C)[C@@]3([H])CC[C@]12C)[C@H](C)[C@@]1([H])CC(C)=C(C)C(=O)O1
• Target: Others

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

14236711