WIN site inhibitor 1 TFA (2407457-36-5 free base)

SKU: orb1708221

Description

WIN site inhibitor 1 TFA is a potent small molecule antagonist of the WDR5 WIN site, exhibiting a dissociation constant (Kd) of 0.1 nM. It is a valuable chemical probe for disrupting protein-protein interactions in chromatin complexes, enabling research into epigenetic regulation and cancer biology in both cellular and biochemical assays.

Research Area

Immunology & Inflammation; Epigenetics & Chromatin; Pharmacology & Drug Discovery

Key Properties

• MW: 612.4
• Formula: C₂₇H₂₃Cl₂F₄N₅O₃
• SMILES: ClC1=CC=C(CNC(C2=CC(CN3C(N(C)C=C3)=N)=CC(C4=C(C)N=C(F)C=C4)=C2)=O)C=C1Cl.O=C(O)C(F)(F)F
• Target: Others

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

146025951