Wilforine

SKU: orb1300231

Description

Wilforine is a bioactive sesquiterpene pyridine alkaloid from Tripterygium wilfordii with demonstrated anti-fibrotic and anti-inflammatory properties, linked to the suppression of TNF-α, IL-6, and NO. Its bioactivity extends to insecticidal effects via Na+/K+-ATPase inhibition, supporting applications in pulmonary fibrosis research and neuropharmacological studies both in vitro and in vivo.

Research Area

Pharmacology & Drug Discovery

Key Properties

• CAS Number: 11088-09-8
• MW: 867.85
• Purity: 99.85% (May vary between batches)
• Formula: C₄₃H₄₉NO₁₈
• SMILES: CC1CCc2ncccc2C(=O)OCC2(C)OC34C(OC(C)=O)C2C(OC(C)=O)C(OC(C)=O)C3(COC(C)=O)C(OC(C)=O)C(OC(=O)c2ccccc2)C(OC1=O)C4(C)O
• Target: ATPase
• Solubility: DMSO:50 mg/mL (57.61 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (2.3 mM)

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Na+/K+-ATPase, inhibit, Inhibitor, Wilforine

Compound Identifiers

PubChem CID

601100