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Catalog Number | orb1302678 |
---|---|
Category | Small Molecules |
Description | WHI-P97 HCl 211555-05-4(free base) |
Purity | 99.49% |
MW | 491.56 |
Biological Activity | WHI-P97 HCl is a potent and selective JAK-3 inhibitor. WHI-P97 had an estimated Ki value of 0.09 microM from modeling studies and a measured IC50 value of 2.5 microM in EGFR kinase inhibition assays. WHI-P97 effectively inhibited the in vitro invasiveness of EGFR-positive human cancer cells in a concentration-dependent manner. |
Formula | C16H14Br2ClN3O3 |
SMILES | COC1=C(C=C2C(=C1)C(=NC=N2)NC3=CC(=C(C(=C3)Br)O)Br)OC.Cl |
Storage | -20°C |
Note | For research use only |
> 98% (HPLC) | |
—— | |
491.6 | |
C16H14Br2ClN3O3 |