WH-4-025

SKU: orb1298270

Description

WH-4-025 is a potent and selective small molecule inhibitor of Salt-inducible kinases (SIKs). It is a valuable research tool for investigating SIK signaling pathways in both cellular and animal models, particularly in studies of metabolism, inflammation, and bone biology.

Research Area

Epigenetics & Chromatin, Signal Transduction

Key Properties

• CAS Number: 1876463-35-2
• MW: 741.76
• Purity: 99.41% (May vary between batches)
• Formula: C₃₉H₃₈F₃N₇O₅
• SMILES: COc1ccc(N(C(=O)Oc2cc(ccc2C)C(=O)Nc2cccc(c2)C(F)(F)F)c2ccnc(Nc3ccc(cc3)N3CCN(C)CC3)n2)c(OC)c1
• Target: SIK,AMPK
• Solubility: DMSO:125 mg/mL (168.52 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (5.39 mM)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Salt-inducible Kinase (SIK), WH-4-025, WH 4 025, WH4025, SIK, Inhibitor, inhibit

Compound Identifiers

PubChem CID

73707529