WEE1-IN-12

SKU: orb3135037

Description

WEE1-IN-12 (Compound 87) is a Wee1 kinase inhibitor with an IC50 of 2.0 nM. It inhibits the proliferation of HT29 cells (IC50: 1.07 μM) and shows enhanced efficacy when combined with Gemcitabine (IC50: 0.34 μM). WEE1-IN-12 is applicable in the study of tumors such as colon cancer.

Research Area

Cancer Biology, Cell Biology

Key Properties

• CAS Number: 3069940-37-7
• MW: 801.68
• Formula: C₃₈H₃₈Cl₂N₁₀O₆
• SMILES: O=C(NC=1C(Cl)=CC=CC1Cl)C2=CN=C(N=C2OC3CC3)NC=4C=NN(C4)C5CCN(CCCNC6=CC=CC=7C(=O)N(C(=O)C67)C8C(=O)NC(=O)CC8)CC5
• Target: Wee1

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

Wee1