WDR5-IN-5

SKU: orb1686274

Description

WDR5-IN-5 is a potent, selective, and orally bioavailable small molecule inhibitor of the WDR5 WIN site, with sub-nanomolar binding affinity (Ki<0.02 nM). It demonstrates anti-proliferative activity in cancer cell-based assays and has shown a favorable pharmacokinetic profile in preclinical studies, supporting its use in oncology research.

Research Area

Epigenetics & Chromatin

Key Properties

• CAS Number: 2417012-26-9
• MW: 534.58
• Formula: C₂₉H₂₉F₃N₆O
• SMILES: C(F)(F)(F)C=1C(C2=C3C(C(=O)N([C@@H]([C@H]4CC4)C5=CC(C)=CC=N5)CC3)=CC(CN6C=CN=C6)=C2)=CN(CC)N1
• Target: Histone Methyltransferase,Others

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

153572662