WDR5-IN-4

SKU: orb1708222

Description

This compound is a potent and selective inhibitor of the WDR5 WIN site, exhibiting sub-nanomolar binding affinity (Kd = 0.1 nM). It serves as a valuable chemical probe for investigating chromatin regulation in cancer biology, with utility in both in vitro biochemical assays and in vivo preclinical cancer models.

Research Area

Cardiovascular Research, Epigenetics & Chromatin, Signal Transduction, Stem Cell & Developmental Biology

Key Properties

• CAS Number: 2407457-36-5
• MW: 498.38
• Formula: C₂₅H₂₂Cl₂FN₅O
• SMILES: CC1=C(C2=CC(CN3C(=N)N(C)C=C3)=CC(C(NCC4=CC(Cl)=C(Cl)C=C4)=O)=C2)C=CC(F)=N1
• Target: Histone Methyltransferase,Others,JAK

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

138319680