WDR5-0103 hydrochloride[890190-22-4(free base)]

SKU: orb1302056

Description

WDR5-0103 hydrochloride (free base 890190-22-4) is a potent and specific WDR5 antagonist with a Kd of 450 nM. This compound is a valuable chemical probe for studying WDR5 function in epigenetic regulation, cancer biology, and stem cell research in both cellular and biochemical assays.

Research Area

Cardiovascular Research, Epigenetics & Chromatin, Signal Transduction, Stem Cell & Developmental Biology

Key Properties

• MW: 419.9
• Purity: 99.81% (May vary between batches)
• Formula: C₂₁H₂₆ClN₃O₄
• SMILES: Cl.COC(=O)c1ccc(N2CCN(C)CC2)c(NC(=O)c2cccc(OC)c2)c1
• Target: JAK
• Solubility: DMSO:50 mg/mL (119.08 mM);Ethanol:18 mg/mL (42.87 mM);H2O:Insoluble

Bioactivity

• Target IC50:
  WDR5:450 nM (Kd)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

WDR50103 hydrochloride[890190224(free base)], WDR-5-0103 hydrochloride[890190-22-4(free base)], WD-Repeat Protein 5-0103, WDR5, WDR5 0103 hydrochloride[890190 22 4(free base)], WDR5-0103 hydrochloride[890190-22-4(free base)]

Compound Identifiers

PubChem CID

139026901