WAY208466 dihydrochloride

SKU: orb1703923

Description

WAY208466 dihydrochloride

Research Area

Neuroscience, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 1207064-61-6
• MW: 420.33
• Purity: 99.56% (May vary between batches)
• Formula: C₁₇H₂₀Cl₂FN₃O₂S
• SMILES: O=S(C1=CC(F)=CC=C1)(C2=CN(CCN(C)C)C3=C2C=CC=N3)=O.Cl.Cl
• Target: 5-HT Receptor
• Solubility: DMSO:80 mg/mL (190.33 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (7.85 mM)

Bioactivity

• In Vivo:
  METHODS: Rats were treated with WAY-208466 (10 mg/kg, subcutaneously, daily, for 14 days) to evaluate the neurochemical effects of chronic 5-HT 6 receptor stimulation. RESULTS: WAY-208466 resulted in a robust and significant increase in extracellular GABA levels.
  Read more...
• In Vitro:
  WAY-208466 binds to the human 5-HT6 receptor with high affinity (Kiz value 4.8 nM) and acts as a full receptor agonist (EC50 value 7.3 nM; Emax value 100%).
  Read more...

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

WAY208466, WAY-208466, WAY 208466, WAY 208466 dihydrochloride, 5HT Receptor, 5-HT6, 5HTReceptor

Compound Identifiers

PubChem CID

22028182