WAY-118959-A

SKU: orb1689834

Description

WAY-118959-A (GM-90257) is a small molecule competitive inhibitor of αTAT1 that binds α-tubulin to suppress microtubule acetylation. It has been shown to induce apoptosis in MDA-MB-231 cells in vitro and demonstrates antitumor efficacy by attenuating tumor growth in vivo, making it a useful research tool for studying tubulin acetylation in cancer biology.

Research Area

Cell Biology, Epigenetics & Chromatin, Molecular Biology, Signal Transduction

Key Properties

• CAS Number: 315703-81-2
• MW: 342.44
• Purity: 99.86% (May vary between batches)
• Formula: C₁₆H₁₄N₄OS₂
• SMILES: COC1=CC=C(NC2=NC(=CS2)C2=C(C)N=C3SC=CN23)C=C1
• Target: JNK,PARP,Microtubule Associated,Bcl-2 Family,Apoptosis
• Solubility: DMSO:11 mg/mL (32.12 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (2.92 mM)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

MicrotubuleAssociated, Microtubule Associated, GM-90257, WAY 118959 A, WAY118959A, WAY-118959-A

Compound Identifiers

PubChem CID

2877425