W23-1006

SKU: orb2945059

Description

W23-1006 is a potent, selective covalent inhibitor of ALKBH5, targeting the C200 residue with an IC50 of 3.848 µM. It demonstrates high selectivity over FTO and ALKBH3. This compound is a valuable research tool for studying m6A demethylase biology and has been applied in triple-negative breast cancer (TNBC) research in vitro.

Research Area

Cardiovascular Research, Cell Biology, Signal Transduction

Key Properties

• CAS Number: 3035498-92-8
• MW: 418.2
• Formula: C₁₇H₁₂BrN₃O₅
• SMILES: O=C1NN(C2=CC=C(C=C2)OC)C(C1=CC3=CC(Br)=CC([N+]([O-])=O)=C3)=O
• Target: ALK

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

175546889