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W1131

SKU: orb1744070

Description

W1131 is a potent STAT3 inhibitor that induces ferroptosis and inhibits tumor growth in models such as gastric cancer cell lines, organoids, and PDX models. It also reverses 5-FU resistance by modulating the IL6-JAK-STAT3 pathway, cell cycle, and oxidative phosphorylation, making it a valuable tool for oncology and drug resistance research.

Research Area

Cell Biology, Signal Transduction, Stem Cell & Developmental Biology

Images & Validation

Key Properties

CAS Number2740522-79-4
MW429.43
FormulaC23H19N5O4
SMILESN(C(=O)C=1OC(N(=O)=O)=CC1)C2=CC=C(C=3N4C(C=C(C=C4)C=5CCNCC5)=NC3)C=C2
TargetOthers,STAT,OXPHOS,Ferroptosis

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Quality Guarantee

Quality Guarantee

Explore bioreagents carefree to elevate your research. All our products are rigorously tested for performance. If a product does not perform as described on its datasheet, our scientific support team will provide expert troubleshooting, a prompt replacement, or a refund. For full details, please see our Terms & Conditions and Buying Guide. Contact us at [email protected].

Key Properties

No computed properties available.

Protocol Information