VX-150

SKU: orb1297950

Description

VX-150 is a potent and selective small molecule inhibitor of the NaV1.8 sodium channel, demonstrating over 400-fold selectivity against other subtypes. This selectivity makes it a valuable research tool for investigating NaV1.8's role in pain signaling, both in cellular assays and in vivo models of neuropathic and inflammatory pain.

Research Area

Pharmacology & Drug Discovery

Key Properties

• CAS Number: 1793080-72-4
• MW: 516.34
• Purity: 97.58% (May vary between batches)
• Formula: C₂₁H₁₇F₄N₂O₇P
• SMILES: O(C1=C(C(NC2=CC(=O)N(COP(=O)(O)O)C=C2)=O)C=CC(C(F)(F)F)=C1)C3=C(C)C=C(F)C=C3
• Target: Sodium Channel
• Solubility: 10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (7.75 mM);DMSO:125 mg/mL (242.09 mM)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Inhibitor, orally, Na+ channels, Na channels, Nav1.8 channel, indications, inhibit, pain, SodiumChannel, Sodium Channel, VX 150, VX150, VX-150

Compound Identifiers

PubChem CID

118126601