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VX-11e

SKU: orb1223724

Description

A potent, selective, and orally bioavailable inhibitor of ERK2 with Ki of 200-fold selectivity over GSK3, Aurora A, CDK2, FLT3, etc; significantly inhibits CKAP2 overexpression-induced cell proliferation, migration and invasion in SiHa cells.

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Key Properties

CAS Number896720-20-0
MW500.3523
Purity>98% (HPLC)
FormulaC24H20Cl2FN5O2
SMILESO=C(C1=CC(C2=NC(NC3=CC=C(F)C=C3Cl)=NC=C2C)=CN1)N[C@@H](C4=CC=CC(Cl)=C4)CO
TargetERK
Solubility10 mM in DMSO

Storage & Handling

StorageStorage temperature: -20°C. Stability: ≥ 2 years
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

VX 11e

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Protocol Information

VX-11e (orb1223724)

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Available Sizes

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200 mg
500 mg
2 mg
$ 100.00
5 mg
$ 150.00
10 mg
$ 190.00
25 mg
$ 340.00
50 mg
$ 510.00
100 mg
$ 780.00