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VVD-442

SKU: orb3136799

Description

VVD-442 is a covalent RAS-PI3K inhibitor that binds covalently to cysteine at position 242 in the RAS-binding domain of PI3Kp110α, thereby inhibiting the interaction between RAS and PI3K. VVD-442 is applicable for research in cancers such as breast cancer.

Research Area

Signal Transduction

Images & Validation

Key Properties

CAS Number3055318-88-9
MW607.94
FormulaC23H25BrClFN2O5S2
SMILESS(=O)(=O)(C1=C(C=C(Br)C=C1)C2=C(Cl)C=CC=C2)N3CCC(C(N[C@@H](/C=C\S(C)(=O)=O)C)=O)(F)CC3
TargetPI3K,Ras

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Protocol Information