VVD-214

SKU: orb2282954

Description

VVD-214 (RO7589831) is a small molecule inhibitor targeting the WRN deconjugating enzyme, blocking its ATPase and deconjugating activities. This lethal variant inhibitor is a research tool for studying proliferative diseases, including cancer, in both in vitro and in vivo experimental models.

Research Area

Cell Biology, Molecular Biology

Key Properties

• CAS Number: 3026500-20-6
• MW: 437.46
• Purity: ≥98% (May vary between batches)
• Formula: C₂₀H₂₁F₂N₃O₄S
• SMILES: O(C=1C(C(N[C@H](/C=C/S(C)(=O)=O)C2CC2)=O)=CN=C(C(C)(F)F)N1)C3=CC=CC=C3
• Target: DNA/RNA Synthesis
• Solubility: 10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (7.54 mM);DMSO:80 mg/mL (182.87 mM)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

DNA Synthesis, DNA/RNA Synthesis, DNASynthesis, VVD133214, VVD-133214, VVD214, RNA Synthesis, RO7589831, RO-7589831, RNASynthesis

Compound Identifiers

PubChem CID

170717998