VUF-6884

SKU: orb3211328

Description

VUF-6884 (Compound 7j) is a ligand for the histamine receptor, exhibiting activity at human H4R and H1R. It demonstrates a pEC50 of 7.70 and a pKi of 7.55 at human H4R, and a pEC50 of 8.17 and a pKi of 8.11 at human H1R. VUF-6884 competitively binds to the orthosteric site of human H4R, replacing histamine, and acts as an inverse agonist at human H1R.

Key Properties

• CAS Number: 3455-10-5
• MW: 327.81
• Formula: C₁₈H₁₈ClN₃O
• SMILES: ClC1=CC=C2N=C(C=3C=CC=CC3OC2=C1)N4CCN(C)CC4
• Target: Histamine Receptor

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

Histamine Receptor